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Obdoc2001 Obdoc2001 Board Certified Obstetrician/Gynecologist in Maryland.
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Obdoc2001 · @Obdoc2001 ·
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27

The risk of getting a COVID-19 infection from contaminated surfaces is extremely low, according to the CDC.

The CDC says risk of COVID-19 transmission on surfaces 1 in 10,000.

The CDC guidance is the strongest argument yet against what some critics have dubbed "hygiene theater."

"There is little scientific support for routine use of disinfectants in community settings, whether indoor or outdoor, to prevent SARS-CoV-2 transmission from fomites," the CDC said.

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Obdoc2001 · @Obdoc2001 ·
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35

A food preservative used to prolong the shelf life of Pop-Tarts, Rice Krispies Treats, Cheez-Its and almost 1,250 other popular processed foods may harm the immune system.
TBHQ is a preservative that is pervasive in processed foods. It has been used in foods for many decades and serves no function besides increasing a product’s shelf life. Using new non-animal test results from ToxCast, EWG found that TBHQ affected immune cell proteins at doses similar to those that cause harm in traditional studies. Earlier studies have found that TBHQ might influence how well flu vaccines work and may be linked to a rise in food allergies.
(tert-butylhydroquinone, or TBHQ)

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Obdoc2001 · @Obdoc2001 ·
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35

200 ml (approximately 1 cup) milk intake per day was associated with a lower risk of cardiovascular disease, stroke, hypertension, colorectal cancer, metabolic syndrome, obesity and osteoporosis. Beneficial associations were also found for type 2 diabetes mellitus and Alzheimer's disease.

Conversely, milk intake might be associated with higher risk of prostate cancer, Parkinson's disease, acne and Fe-deficiency anemia in infancy.

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35
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Obdoc2001 · @Obdoc2001 ·
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37

They found the mortality rate among participants without MRSA was about 18%, but among those with colonized MRSA, the mortality rate was 36%. Participants who carried staph bacteria on their skin, but not MRSA, did not have an increased risk for premature death.
Some states and hospital systems require MRSA testing for patients before hospital admission, but policies for testing and treatment of colonized MRSA, which may include use of topical or oral antibiotics, are highly variable from hospital to hospital.

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37

A third of Americans carry Staphylococcus aureus, or staph, on their skin or in nasal passages. About 1% of those people, or more than 3 million people, carry MRSA, the staph strain that is hard to treat and resistant to many antibiotics. Unless MRSA carriers develop an infection or are tested for the bacteria, they may not even know they carry it. Previous research has found that a quarter of people who carry MRSA without an active infection, known as colonized MRSA, for a year or more will eventually develop a MRSA infection.

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37

A University of Florida study of middle-aged and older adults finds those who unknowingly carry methicillin-resistant Staphylococcus aureus, or MRSA, on their skin are twice as likely to die within the next decade as people who do not have the bacteria.
"Very few people who carry MRSA know they have it, yet we have found a distinct link between people with undetected MRSA and premature death," said the study's lead author Arch G. Mainous III, PhD
The findings suggest that routine screening for undetected MRSA may be warranted in older people to prevent deaths from infection.

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40

Reports indicate that 43% of adults with depression are obese and that adults with mental illness are more likely to develop obesity than those who are mentally healthy.
Factors such as hormonal dysregulation, genetic deficiency and inflammation have been proposed to be involved in the connection between obesity and mental disorders. Here we provide evidence that supports the involvement of a neural component
The researchers state that their results provide convincing support for further studies and future clinical trials testing the value of a cocktail therapy combining zonisamide and granisetron (or a selection of their derivatives) to treat metabolic-psychiatric diseases."

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38

Interestingly, weight loss was not the result of lack of appetite, but of the animals' change of food preference. Before the treatment, the mice naturally preferred to eat a high-fat diet, but after the treatment they turned their preference toward a healthier diet with reduced fat and abundant protein and carbohydrates. The findings, published in the journal Molecular Psychiatry, for the first time, not only reveal a key regulatory mechanism for coinciding obesity and mental disorders, but also suggest the possibility of a pharmacological treatment.

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38

Research has found that obesity and mental disorders such as depression and anxiety seem to often go hand in hand. Researchers at Baylor College of Medicine and collaborating institutions are providing new insights into this association by identifying and characterizing a novel neural circuit that mediates the reciprocal control of feeding and psychological states in mouse models.

Similar to human patients, mice that consumed a high-fat diet not only became obese, but also anxious and depressed, a condition mediated by a defective brain circuit. When the researchers genetically or pharmacologically corrected specific disruptions they had observed within this circuit, the mice became less anxious and depressed and later lost excess body weight.

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38

The review shows that there is limited evidence to support or refute their use for the management of any pain condition. The studies we found were poor quality (high risk of bias) and the evidence was of very low-certainty, meaning that we are very uncertain of the findings and more research is needed.

For many this will be an unpopular conclusion, but we need to face up to the fact that the evidence is simply lacking. Science is not about popularity but keeping people safe from false claims.

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38

Their findings suggest that although there is preclinical data supporting the hypothesis of cannabinoid analgesia, uncertainties especially in clinical evidence, imply the evidence base for efficacy and safety does not reach the threshold required for the IASP to endorse their general use for pain control. The studies and the statement from the IASP are limited to the use of cannabinoids to treat pain, and not for other conditions for which cannabinoids are used.

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39

The study reports within 12 months since first cannabis use, 10.7% of adolescents had cannabis use disorder; within 12 months since first misuse of prescription drugs: 11.2% of adolescents had prescription opioid use disorder, 13.9% of adolescents had prescription stimulant use disorder, 11.2% of adolescents had prescription tranquilizer use disorder.

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39

A study led by the National Institute on Drug Abuse (NIDA) claims that adolescents (ages 12-17) are more likely to develop a substance abuse disorder after trying marijuana or misusing prescription drugs.

"Research has shown that brain development continues into a person’s 20s, and that age of drug initiation is a very important risk factor for developing addiction," said Emily B. Einstein, Ph.D., chief of NIDA’s Science Policy Branch and a co-author of the study. "This underscores the importance of drug use prevention and screening for substance use or misuse among adolescents and young adults. Offering timely treatment and support to young people who need it must be a public health priority."

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39

Although it might be feasible for some people to practice methionine restriction, for example, by adhering to a vegan diet, such a diet might not be practical or desirable for everyone.
It might be more feasible to develop an intervention that produces the same effects as methionine restriction, while also allowing an individual to eat a normal, unrestricted diet.
Methionine restriction causes a reduction in IGF-1.
Selenium supplementation completely protected against the dramatic weight gain and fat accumulation seen in mice fed the control diet, and to the same extent as restricting methionine.
Selenium supplementation produces most, if not all, of the hallmarks of methionine restriction, which suggests that this intervention may have a similar positive effect on health span.

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Impressions
39

Adding the nutrient selenium to diets protects against obesity and provides metabolic benefits to mice, according to a study published today in eLife.
One of the proven methods of increasing healthspan in many organisms, including non-human mammals, is to restrict dietary intake of an amino acid called methionine.
Recent studies have suggested that the effects of methionine restriction on healthspan are likely to be conserved in humans.

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Obdoc2001 · @Obdoc2001 ·
Impressions
40

Makers of inhalers that contain the nasal decongestant propylhexedrine should make design changes to prevent misuse, the U.S. Food and Drug Administration says.

Propylhexedrine is a nasal decongestant in over-the-counter inhalers and right now is “only marketed under the brand name Benzedrex,” the FDA said. The agency said that propylhexedrine is effective and safe when used for short periods as directed for relief of congestion due to colds, hay fever, or other upper respiratory allergies. But misuse can bring dangers.
“Benzedrex inhalers can be legally purchased, but propylhexedrine abuse occurs as people try to find legal ways to get high or increase productivity and concentration,” according to the National Capital Poison Center. “There have been many reports of toxicity associated with propylhexedrine extracted from an inhaler and swallowed or injected. Swallowing the contents of one propylhexedrine inhaler has caused heart attack and lung injury in adults and children.”

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40

Eliminating meat from a terrible diet doesn’t really make it any healthier. One 2017 study found that participants whose mostly-plant-based diets (think vegetarian or vegan) included a lot of processed foods, such as sugary beverages and French fries, were more likely to develop heart disease or die during the study period than people who avoided processed food—even if that meant eating a little meat.

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40

New research led by a University of Georgia faculty member in collaboration with a University of Southern California research group has shown in a rodent model that daily consumption of sugar-sweetened beverages during adolescence impairs performance on a learning and memory task during adulthood.

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Obdoc2001 · @Obdoc2001 ·
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40

The Youngest Saint

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